# Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women

> **NCT03018366** · PHASE2 · COMPLETED · sponsor: **Cedars-Sinai Medical Center** · enrollment: 29 (actual)

## Conditions studied

- Estrogen Deficiency
- Cardiovascular Disease (CVD)
- Functional Hypothalamic Amenorrhea
- Endothelial Dysfunction

## Interventions

- **DRUG:** 17beta Estradiol
- **DRUG:** Transdermal placebo patch
- **DRUG:** Progesterone
- **DRUG:** Placebo Pill

## Key facts

- **NCT ID:** NCT03018366
- **Lead sponsor:** Cedars-Sinai Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-01-01
- **Primary completion:** 2023-02-01
- **Final completion:** 2023-02-01
- **Target enrollment:** 29 (ACTUAL)
- **Last updated:** 2025-03-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03018366

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03018366, "Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT03018366. Licensed CC0.

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