# Familial Investigations of Childhood Cancer Predisposition

> **NCT03050268** · — · RECRUITING · sponsor: **St. Jude Children's Research Hospital** · enrollment: 1500 (estimated)

## Conditions studied

- Acute Leukemia
- Adenomatous Polyposis
- Adrenocortical Carcinoma
- AML
- BAP1 Tumor Predisposition Syndrome
- Carney Complex
- Choroid Plexus Carcinoma
- Constitutional Mismatch Repair Deficiency Syndrome
- Diamond-Blackfan Anemia
- DICER1 Syndrome
- Dyskeratosis Congenita
- Emberger Syndrome
- Familial Acute Myeloid Leukemia
- Familial Adenomatous Polyposis
- Fanconi Anemia
- Familial Cancer
- Familial Wilms Tumor
- Familial Neuroblastoma
- GIST
- Hereditary Breast and Ovarian Cancer
- Hereditary Paraganglioma-Pheochromocytoma Syndrome
- Hodgkin Lymphoma
- Juvenile Polyposis
- Li-Fraumeni Syndrome
- Lynch Syndrome
- MDS
- Melanoma Syndrome
- Multiple Endocrine Neoplasia Type 1
- Multiple Endocrine Neoplasia Type 2
- Neuroblastoma
- Neurofibromatosis Type 1
- Neurofibromatosis Type II
- Nevoid Basal Cell Carcinoma Syndrome
- Non Hodgkin Lymphoma
- Noonan Syndrome and Other Rasopathy
- Overgrowth Syndromes
- Pancreatic Cancer
- Peutz-Jeghers Syndrome
- Pheochromocytoma/Paraganglioma
- PTEN Hamartoma Tumor Syndrome
- Retinoblastoma
- Rhabdoid Tumor Predisposition Syndrome
- Rhabdomyosarcoma
- Rothmund-Thomson Syndrome
- Tuberous Sclerosis
- Von Hippel-Lindau Disease

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT03050268
- **Lead sponsor:** St. Jude Children's Research Hospital
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2017-04-06
- **Primary completion:** 2037-03-31
- **Final completion:** 2037-03-31
- **Target enrollment:** 1500 (ESTIMATED)
- **Last updated:** 2026-04-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03050268

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03050268, "Familial Investigations of Childhood Cancer Predisposition". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT03050268. Licensed CC0.

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