# Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Duodenal Ulcer Participants With or Without Helicobacter Pylori Infection

> **NCT03050359** · PHASE3 · COMPLETED · sponsor: **Takeda** · enrollment: 533 (actual)

## Conditions studied

- Duodenal Ulcer

## Interventions

- **DRUG:** TAK-438
- **DRUG:** Lansoprazole
- **DRUG:** TAK-438 Placebo
- **DRUG:** Lansoprazole Placebo
- **DRUG:** Bismuth-Containing Quadruple Therapy

## Key facts

- **NCT ID:** NCT03050359
- **Lead sponsor:** Takeda
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-04-05
- **Primary completion:** 2019-03-19
- **Final completion:** 2019-07-19
- **Target enrollment:** 533 (ACTUAL)
- **Last updated:** 2020-06-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03050359

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03050359, "Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Duodenal Ulcer Participants With or Without Helicobacter Pylori Infection". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT03050359. Licensed CC0.

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