# A Study of Pleiotropic Pioglitazone Effects on the Alcoholic Lung (APPEAL Study)

> **NCT03060772** · PHASE2 · TERMINATED · sponsor: **Emory University** · enrollment: 50 (actual)

## Conditions studied

- Alcoholism

## Interventions

- **DRUG:** Pioglitazone

## Key facts

- **NCT ID:** NCT03060772
- **Lead sponsor:** Emory University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2018-01-03
- **Primary completion:** 2020-01-28
- **Final completion:** 2020-01-28
- **Target enrollment:** 50 (ACTUAL)
- **Why stopped:** Study was suspended in 2020 due to COVID-19 pandemic as a result of recruitment challenges and the inability to conduct all study procedures (e.g., bronchoscopy) per protocol. In late 2021 the decision was made to not re-open the study.
- **Last updated:** 2023-02-14

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03060772

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03060772, "A Study of Pleiotropic Pioglitazone Effects on the Alcoholic Lung (APPEAL Study)". Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/clinical/NCT03060772. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
