# Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma

> **NCT03063632** · PHASE2 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 28 (actual)

## Conditions studied

- Metastatic Myxoid Liposarcoma
- Metastatic Round Cell Liposarcoma
- Metastatic Synovial Sarcoma
- Recurrent Mycosis Fungoides and Sezary Syndrome
- Refractory Mycosis Fungoides and Sezary Syndrome
- Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v7
- Stage II Mycosis Fungoides and Sezary Syndrome AJCC v7
- Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v7
- Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v7
- Stage III Mycosis Fungoides and Sezary Syndrome AJCC v7
- Stage IIIA Mycosis Fungoides and Sezary Syndrome AJCC v7
- Stage IIIB Mycosis Fungoides and Sezary Syndrome AJCC v7
- Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v7
- Stage IVA Mycosis Fungoides and Sezary Syndrome AJCC v7
- Stage IVB Mycosis Fungoides and Sezary Syndrome AJCC v7
- Unresectable Synovial Sarcoma

## Interventions

- **BIOLOGICAL:** Interferon Gamma-1b
- **OTHER:** Laboratory Biomarker Analysis
- **BIOLOGICAL:** Pembrolizumab

## Key facts

- **NCT ID:** NCT03063632
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-12-14
- **Primary completion:** 2021-04-08
- **Final completion:** 2023-03-14
- **Target enrollment:** 28 (ACTUAL)
- **Last updated:** 2023-10-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03063632

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03063632, "Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT03063632. Licensed CC0.

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