# Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors

> **NCT03074513** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **M.D. Anderson Cancer Center** · enrollment: 133 (actual)

## Conditions studied

- Appendix Adenocarcinoma
- Human Papillomavirus-Related Anal Squamous Cell Carcinoma
- Human Papillomavirus-Related Cervical Squamous Cell Carcinoma
- Human Papillomavirus-Related Squamous Cell Carcinoma of the Penis
- Human Papillomavirus-Related Vulvar Squamous Cell Carcinoma
- Neuroendocrine Carcinoma
- Pancreatic Neuroendocrine Tumor
- Recurrent Merkel Cell Carcinoma
- Recurrent Nasopharynx Carcinoma
- Recurrent Peritoneal Malignant Mesothelioma
- Recurrent Pleural Malignant Mesothelioma
- Stage III Merkel Cell Carcinoma AJCC v7
- Stage III Nasopharyngeal Carcinoma AJCC v7
- Stage III Pleural Malignant Mesothelioma AJCC v7
- Stage IV Merkel Cell Carcinoma AJCC v7
- Stage IV Nasopharyngeal Carcinoma AJCC v7
- Stage IV Pleural Malignant Mesothelioma AJCC v7
- Stage IVA Nasopharyngeal Carcinoma AJCC v7
- Stage IVB Nasopharyngeal Carcinoma AJCC v7
- Stage IVC Nasopharyngeal Carcinoma AJCC v7
- Vaginal Squamous Cell Carcinoma, Not Otherwise Specified

## Interventions

- **DRUG:** Atezolizumab
- **BIOLOGICAL:** Bevacizumab
- **OTHER:** Laboratory Biomarker Analysis
- **OTHER:** Pharmacological Study

## Key facts

- **NCT ID:** NCT03074513
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2017-03-03
- **Primary completion:** 2027-09-30
- **Final completion:** 2027-09-30
- **Target enrollment:** 133 (ACTUAL)
- **Last updated:** 2026-03-11

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03074513

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03074513, "Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT03074513. Licensed CC0.

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