# The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor

> **NCT03085485** · PHASE2 · COMPLETED · sponsor: **University of Alabama at Birmingham** · enrollment: 40 (actual)

## Conditions studied

- Chronic Obstructive Pulmonary Disease
- Chronic Bronchitis

## Interventions

- **DRUG:** Ivacaftor 150 MG
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT03085485
- **Lead sponsor:** University of Alabama at Birmingham
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-03-16
- **Primary completion:** 2022-09-30
- **Final completion:** 2022-09-30
- **Target enrollment:** 40 (ACTUAL)
- **Last updated:** 2024-12-12

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03085485

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03085485, "The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT03085485. Licensed CC0.

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