# A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

> **NCT03085914** · PHASE1,PHASE2 · COMPLETED · sponsor: **Incyte Corporation** · enrollment: 70 (actual)

## Conditions studied

- Solid Tumor

## Interventions

- **DRUG:** Epacadostat
- **DRUG:** Pembrolizumab
- **DRUG:** Oxaliplatin
- **DRUG:** Leucovorin
- **DRUG:** 5-Fluorouracil
- **DRUG:** Gemcitabine
- **DRUG:** nab-Paclitaxel
- **DRUG:** Carboplatin
- **DRUG:** Paclitaxel
- **DRUG:** Pemetrexed
- **DRUG:** Cyclophosphamide
- **DRUG:** Carboplatin
- **DRUG:** Cisplatin
- **DRUG:** 5-Fluorouracil
- **DRUG:** Investigator's choice of platinum agent

## Key facts

- **NCT ID:** NCT03085914
- **Lead sponsor:** Incyte Corporation
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-05-02
- **Primary completion:** 2019-01-25
- **Final completion:** 2020-07-13
- **Target enrollment:** 70 (ACTUAL)
- **Last updated:** 2022-09-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03085914

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03085914, "A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)". Retrieved via AI Analytics 2026-07-13 from https://api.ai-analytics.org/clinical/NCT03085914. Licensed CC0.

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