# APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery

> **NCT03087591** · PHASE1 · COMPLETED · sponsor: **Wake Forest University Health Sciences** · enrollment: 11 (actual)

## Conditions studied

- Metastatic Malignant Neoplasm in the Brain
- Metastatic Solid Neoplasm
- Recurrent Colorectal Carcinoma
- Recurrent Pancreatic Carcinoma
- Recurrent Solid Neoplasm
- Stage IV Colorectal Cancer
- Stage IV Pancreatic Cancer
- Stage IVA Colorectal Cancer
- Stage IVA Pancreatic Cancer
- Stage IVB Colorectal Cancer
- Stage IVB Pancreatic Cancer
- Unresectable Solid Neoplasm

## Interventions

- **OTHER:** Laboratory Biomarker Analysis
- **BIOLOGICAL:** siRNA-transfected Peripheral Blood Mononuclear Cells (PBMC) APN401

## Key facts

- **NCT ID:** NCT03087591
- **Lead sponsor:** Wake Forest University Health Sciences
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-04-28
- **Primary completion:** 2019-07-31
- **Final completion:** 2020-12-08
- **Target enrollment:** 11 (ACTUAL)
- **Last updated:** 2024-10-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03087591

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03087591, "APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT03087591. Licensed CC0.

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