# Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients

> **NCT03088306** · EARLY_PHASE1 · COMPLETED · sponsor: **Johns Hopkins University** · enrollment: 49 (actual)

## Conditions studied

- Lumbar Spinal Stenosis
- Lumbar Spinal Instability
- Lumbar Spine Degeneration

## Interventions

- **DRUG:** Standard analgesia use [Oxygen]
- **DRUG:** Standard analgesia use [Hydromorphone]
- **DRUG:** Standard analgesia use [Volatile Anesthesia]
- **DRUG:** Standard analgesia use [Fentanyl]
- **DRUG:** Multi-modal pain management [Acetaminophen + Gabapentin]
- **DRUG:** Multi-modal pain management [Fentanyl]
- **DRUG:** Multi-modal pain management [Intravenous Ketamine]
- **DRUG:** Multi-modal pain management [Valium + Gabapentin]

## Key facts

- **NCT ID:** NCT03088306
- **Lead sponsor:** Johns Hopkins University
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-07-01
- **Primary completion:** 2018-05-31
- **Final completion:** 2018-08-31
- **Target enrollment:** 49 (ACTUAL)
- **Last updated:** 2018-10-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03088306

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03088306, "Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT03088306. Licensed CC0.

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