# A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems

> **NCT03098680** · PHASE1 · TERMINATED · sponsor: **Cambridge University Hospitals NHS Foundation Trust** · enrollment: 18 (actual)

## Conditions studied

- Drug-Related Side Effects and Adverse Reactions
- Cardiovascular System Disease

## Interventions

- **DRUG:** Albuterol Sulfate
- **DRUG:** Nicardipine Hydrochloride
- **DRUG:** Dobutamine Hydrochloride
- **DRUG:** Phenylephrine Hydrochloride
- **DRUG:** Verapamil Hydrochloride
- **DRUG:** Phentolamine Mesylate
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT03098680
- **Lead sponsor:** Cambridge University Hospitals NHS Foundation Trust
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2017-04-24
- **Primary completion:** 2020-02-29
- **Final completion:** 2020-02-29
- **Target enrollment:** 18 (ACTUAL)
- **Why stopped:** Unable to recruit in time before end of PhD studentship
- **Last updated:** 2021-03-22

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03098680

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03098680, "A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems". Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/clinical/NCT03098680. Licensed CC0.

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