# Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ionis AGT-LRx in Healthy Volunteers

> **NCT03101878** · PHASE1 · COMPLETED · sponsor: **Ionis Pharmaceuticals, Inc.** · enrollment: 62 (actual)

## Conditions studied

- Healthy Volunteers

## Interventions

- **DRUG:** Ionis AGT-LRx
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT03101878
- **Lead sponsor:** Ionis Pharmaceuticals, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-04-05
- **Primary completion:** 2018-03-29
- **Final completion:** 2018-08-01
- **Target enrollment:** 62 (ACTUAL)
- **Last updated:** 2018-08-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03101878

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03101878, "Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ionis AGT-LRx in Healthy Volunteers". Retrieved via AI Analytics 2026-05-30 from https://api.ai-analytics.org/clinical/NCT03101878. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*