# Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

> **NCT03117751** · PHASE2,PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **St. Jude Children's Research Hospital** · enrollment: 790 (actual)

## Conditions studied

- Acute Lymphoblastic Leukemia
- Acute Lymphoblastic Lymphoma

## Interventions

- **DRUG:** Prednisone
- **DRUG:** Vincristine
- **DRUG:** Daunorubicin
- **DRUG:** Pegaspargase
- **DRUG:** Erwinase®
- **DRUG:** Cyclophosphamide
- **DRUG:** Cytarabine
- **DRUG:** Mercaptopurine
- **DRUG:** Dasatinib
- **DRUG:** Methotrexate
- **DRUG:** Blinatumomab
- **DRUG:** Ruxolitinib
- **DRUG:** Bortezomib
- **DRUG:** Dexamethasone
- **DRUG:** Doxorubicin
- **DRUG:** Etoposide
- **DRUG:** Clofarabine
- **DRUG:** Vorinostat
- **DRUG:** Idarubicin
- **DRUG:** Nelarabine

## Key facts

- **NCT ID:** NCT03117751
- **Lead sponsor:** St. Jude Children's Research Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2017-03-29
- **Primary completion:** 2026-09-30
- **Final completion:** 2028-09-30
- **Target enrollment:** 790 (ACTUAL)
- **Last updated:** 2025-12-05

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03117751

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03117751, "Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma". Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/clinical/NCT03117751. Licensed CC0.

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