# Cortical Stimulation to Treat Mood and Behavioral Symptoms in Parkinson's Disease Patients

> **NCT03131817** · NA · COMPLETED · sponsor: **Simon J. Little, MBBS, PhD** · enrollment: 5 (actual)

## Conditions studied

- Parkinson's Disease

## Interventions

- **DEVICE:** Medtronic Activa PC+S System with Chronic Neural Recording
- **BEHAVIORAL:** Effort-Reward Decision-Making Task
- **OTHER:** Prefrontal Cortex Stimulation
- **BEHAVIORAL:** Tablet-Based Mood Tracking (Immediate Mood Scaler)

## Key facts

- **NCT ID:** NCT03131817
- **Lead sponsor:** Simon J. Little, MBBS, PhD
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-12-16
- **Primary completion:** 2024-06-18
- **Final completion:** 2024-06-18
- **Target enrollment:** 5 (ACTUAL)
- **Last updated:** 2025-11-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03131817

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03131817, "Cortical Stimulation to Treat Mood and Behavioral Symptoms in Parkinson's Disease Patients". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03131817. Licensed CC0.

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