# Shaping Anesthetic Techniques to Reduce Post-operative Delirium

> **NCT03133845** · NA · COMPLETED · sponsor: **Johns Hopkins University** · enrollment: 218 (estimated)

## Conditions studied

- Delirium
- Lumbar Radiculopathy
- Lumbar Osteoarthritis
- Lumbar Spine Disc Degeneration

## Interventions

- **PROCEDURE:** Light sedation with propofol
- **PROCEDURE:** Induction with propofol
- **PROCEDURE:** Maintenance anesthetic using a volatile anesthetic
- **PROCEDURE:** Muscle relaxant during maintenance anesthesia
- **PROCEDURE:** Pain control with fentanyl
- **PROCEDURE:** Bispectral Index (BIS) monitoring for depth of anesthesia
- **PROCEDURE:** Spinal Anesthesia
- **PROCEDURE:** Midazolam administered during spinal anesthesia
- **PROCEDURE:** Cerebrospinal fluid collection
- **PROCEDURE:** Administration of intrathecal morphine

## Key facts

- **NCT ID:** NCT03133845
- **Lead sponsor:** Johns Hopkins University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-10
- **Primary completion:** 2020-05-25
- **Final completion:** 2020-05-25
- **Target enrollment:** 218 (ESTIMATED)
- **Last updated:** 2020-06-18

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03133845

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03133845, "Shaping Anesthetic Techniques to Reduce Post-operative Delirium". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT03133845. Licensed CC0.

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