# Exercise and NO in HFrEF

> **NCT03136029** · EARLY_PHASE1 · COMPLETED · sponsor: **VA Office of Research and Development** · enrollment: 68 (actual)

## Conditions studied

- Heart Failure With Reduced Ejection Fraction

## Interventions

- **DIETARY_SUPPLEMENT:** Antioxidant
- **DIETARY_SUPPLEMENT:** Tetrahydrobiopterin (BH4)
- **OTHER:** Exercise training

## Key facts

- **NCT ID:** NCT03136029
- **Lead sponsor:** VA Office of Research and Development
- **Sponsor class:** FED
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-06-01
- **Primary completion:** 2025-05-31
- **Final completion:** 2025-07-31
- **Target enrollment:** 68 (ACTUAL)
- **Last updated:** 2025-08-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03136029

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03136029, "Exercise and NO in HFrEF". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03136029. Licensed CC0.

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