# Clinical Evaluation of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement (CADENCE)

> **NCT03142958** · — · SUSPENDED · sponsor: **Smith & Nephew, Inc.** · enrollment: 132 (actual)

## Conditions studied

- Rheumatoid Arthritis
- Degenerative Arthritis
- Post Traumatic Arthritis

## Interventions

- **DEVICE:** Integra Cadence Total Ankle System

## Key facts

- **NCT ID:** NCT03142958
- **Lead sponsor:** Smith & Nephew, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** SUSPENDED
- **Start date:** 2017-08-24
- **Primary completion:** 2025-04-30
- **Final completion:** 2025-04-30
- **Target enrollment:** 132 (ACTUAL)
- **Why stopped:** Prematurely terminated -Sponsor decision not due to adverse events, complications, or device issues. Final data collection underway.
- **Last updated:** 2024-11-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03142958

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03142958, "Clinical Evaluation of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement (CADENCE)". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT03142958. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*