# An Efficacy and Safety Study Of Pracinostat In Combination With Azacitidine In Adults With Acute Myeloid Leukemia

> **NCT03151408** · PHASE3 · TERMINATED · sponsor: **Helsinn Healthcare SA** · enrollment: 406 (actual)

## Conditions studied

- Acute Myeloid Leukemia

## Interventions

- **DRUG:** Pracinostat
- **DRUG:** Placebos
- **DRUG:** Azacitidine

## Key facts

- **NCT ID:** NCT03151408
- **Lead sponsor:** Helsinn Healthcare SA
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2017-06-23
- **Primary completion:** 2020-08-20
- **Final completion:** 2020-08-20
- **Target enrollment:** 406 (ACTUAL)
- **Why stopped:** The IDMC recommended to stop the study prematurely due to a lack of efficacy.
- **Last updated:** 2022-03-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03151408

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03151408, "An Efficacy and Safety Study Of Pracinostat In Combination With Azacitidine In Adults With Acute Myeloid Leukemia". Retrieved via AI Analytics 2026-05-30 from https://api.ai-analytics.org/clinical/NCT03151408. Licensed CC0.

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