# Pilot Study to Investigate the Creation of Physiological Rhythm by Closed Loop Stimulation in hEart Failure pAtients With chronoTropic incompEtence

> **NCT03157076** · NA · COMPLETED · sponsor: **Biotronik SE & Co. KG** · enrollment: 30 (actual)

## Conditions studied

- Heart Failure
- CPX

## Interventions

- **DEVICE:** Cardiac Resynchronization therapy device with Closed Loop Stimulation (CLS)

## Key facts

- **NCT ID:** NCT03157076
- **Lead sponsor:** Biotronik SE & Co. KG
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-04-19
- **Primary completion:** 2019-03-31
- **Final completion:** 2019-04-30
- **Target enrollment:** 30 (ACTUAL)
- **Last updated:** 2019-05-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03157076

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03157076, "Pilot Study to Investigate the Creation of Physiological Rhythm by Closed Loop Stimulation in hEart Failure pAtients With chronoTropic incompEtence". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT03157076. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*