# Early Intrapleural TPA Instillation Versus Late

> **NCT03167281** · PHASE4 · WITHDRAWN · sponsor: **Prisma Health-Midlands**

## Conditions studied

- Tissue Plasminogen Activator

## Interventions

- **COMBINATION_PRODUCT:** early tPA and DNase

## Key facts

- **NCT ID:** NCT03167281
- **Lead sponsor:** Prisma Health-Midlands
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2017-02-17
- **Primary completion:** 2021-03-10
- **Final completion:** 2021-03-10
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** lack of adequate recruitment
- **Last updated:** 2025-02-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03167281

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03167281, "Early Intrapleural TPA Instillation Versus Late". Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/clinical/NCT03167281. Licensed CC0.

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