Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer

PHASE2

Phase

TERMINATED

Status

Enrollment

OTHER_GOV

Sponsor class

Stopped Aspirin added to chemoradiotherapy was safe but did not improve response to total neoadjuvant treatment. The study was closed due absence of benefit.

Conditions

Rectal Cancer, Adenocarcinoma
Locally Advanced Malignant Neoplasm
Chemoradiation

Interventions

DRUG: Aspirin
DRUG: Placebo Oral Tablet

Sponsor

Instituto Nacional de Cancer, Brazil