# A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin

> **NCT03174041** · PHASE1 · COMPLETED · sponsor: **Genentech, Inc.** · enrollment: 63 (actual)

## Conditions studied

- Healthy Participants

## Interventions

- **DRUG:** Midazolam
- **DRUG:** GDC-0853
- **DRUG:** Midazolam and GDC-0853
- **DRUG:** Rosuvastatin
- **DRUG:** Rosuvastatin and GDC-0853
- **DRUG:** Simvastatin
- **DRUG:** Simvastatin and GDC-0853
- **DRUG:** GDC-0853
- **DRUG:** Itraconazole
- **DRUG:** GDC-0853 and itraconazole

## Key facts

- **NCT ID:** NCT03174041
- **Lead sponsor:** Genentech, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-04-18
- **Primary completion:** 2017-06-23
- **Final completion:** 2017-06-23
- **Target enrollment:** 63 (ACTUAL)
- **Last updated:** 2019-09-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03174041

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03174041, "A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT03174041. Licensed CC0.

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