# Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia

> **NCT03196180** · EARLY_PHASE1 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 13 (actual)

## Conditions studied

- Cervical Intraepithelial Neoplasia Grade 2/3
- Cervical Squamous Cell Carcinoma In Situ
- Cervical Squamous Intraepithelial Neoplasia 2
- High Grade Cervical Intraepithelial Neoplasia

## Interventions

- **DRUG:** Imiquimod
- **DRUG:** Topical Fluorouracil

## Key facts

- **NCT ID:** NCT03196180
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-10-15
- **Primary completion:** 2020-11-04
- **Final completion:** 2024-08-02
- **Target enrollment:** 13 (ACTUAL)
- **Last updated:** 2025-04-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03196180

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03196180, "Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03196180. Licensed CC0.

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