# GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression

> **NCT03198546** · PHASE1 · RECRUITING · sponsor: **Second Affiliated Hospital of Guangzhou Medical University** · enrollment: 30 (estimated)

## Conditions studied

- Hepatocellular Carcinoma
- Immunotherapy
- CAR
- GPC3 Gene Inactivation
- T Cell
- Squamous Cell Lung Cancer

## Interventions

- **BIOLOGICAL:** GPC3 and/or TGFβ targeting CAR-T cells

## Key facts

- **NCT ID:** NCT03198546
- **Lead sponsor:** Second Affiliated Hospital of Guangzhou Medical University
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2017-07-01
- **Primary completion:** 2029-08-01
- **Final completion:** 2036-08-01
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2024-06-25

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03198546

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03198546, "GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression". Retrieved via AI Analytics 2026-06-07 from https://api.ai-analytics.org/clinical/NCT03198546. Licensed CC0.

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