Atezolizumab With or Without Cobimetinib in Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed by Surgery or Gallbladder Cancer

NCT03201458 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

86

Enrollment

NIH

Sponsor class

Conditions

Gallbladder Carcinoma
Metastatic Cholangiocarcinoma
Stage III Intrahepatic Cholangiocarcinoma AJCC v8
Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
Unresectable Cholangiocarcinoma

Interventions

DRUG: Atezolizumab
PROCEDURE: Biopsy
PROCEDURE: Biospecimen Collection
DRUG: Cobimetinib
PROCEDURE: Computed Tomography
PROCEDURE: Magnetic Resonance Imaging

Sponsor

National Cancer Institute (NCI)