# The Effect of Urea Cream on Sorafenib-associated Hand-Foot Skin Reaction

> **NCT03212625** · PHASE4 · COMPLETED · sponsor: **Korea University Guro Hospital** · enrollment: 288 (actual)

## Conditions studied

- Hepatocellular Carcinoma

## Interventions

- **DRUG:** Urea Cream 20%
- **DRUG:** Placebos

## Key facts

- **NCT ID:** NCT03212625
- **Lead sponsor:** Korea University Guro Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-01-28
- **Primary completion:** 2018-09-20
- **Final completion:** 2018-09-20
- **Target enrollment:** 288 (ACTUAL)
- **Last updated:** 2019-08-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03212625

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03212625, "The Effect of Urea Cream on Sorafenib-associated Hand-Foot Skin Reaction". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT03212625. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*