# N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms

> **NCT03221231** · PHASE4 · UNKNOWN · sponsor: **Universitair Ziekenhuis Brussel** · enrollment: 75 (estimated)

## Conditions studied

- Cannabis Use Disorder
- Cannabis Dependence

## Interventions

- **DRUG:** N-acetylcysteine
- **DRUG:** Placebo Oral Tablet
- **OTHER:** Magnetic Resonance Imaging
- **OTHER:** Neurocognitive measures
- **OTHER:** Neuro-inflammatory measures

## Key facts

- **NCT ID:** NCT03221231
- **Lead sponsor:** Universitair Ziekenhuis Brussel
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2016-05-15
- **Primary completion:** 2022-02-01
- **Final completion:** 2023-02-01
- **Target enrollment:** 75 (ESTIMATED)
- **Last updated:** 2020-12-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03221231

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03221231, "N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms". Retrieved via AI Analytics 2026-05-30 from https://api.ai-analytics.org/clinical/NCT03221231. Licensed CC0.

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