# M3541 in Combination With Radiotherapy in Solid Tumors

> **NCT03225105** · PHASE1 · TERMINATED · sponsor: **EMD Serono Research & Development Institute, Inc.** · enrollment: 15 (actual)

## Conditions studied

- Solid Tumors

## Interventions

- **DRUG:** M3541
- **RADIATION:** Palliative Radiotherapy (RT)

## Key facts

- **NCT ID:** NCT03225105
- **Lead sponsor:** EMD Serono Research & Development Institute, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2017-09-06
- **Primary completion:** 2019-09-02
- **Final completion:** 2020-04-27
- **Target enrollment:** 15 (ACTUAL)
- **Why stopped:** The study was terminated early per sponsor decision to halt further development of M3541 due to pharmaceutical and PK/pharmacodynamics properties that precluded further clinical development.
- **Last updated:** 2023-11-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03225105

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03225105, "M3541 in Combination With Radiotherapy in Solid Tumors". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT03225105. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*