# Changes in PPV Induced by PLR Test to Predict Fluid Responsiveness in ICU

> **NCT03225378** · — · COMPLETED · sponsor: **Centre Hospitalier Arras** · enrollment: 286 (actual)

## Conditions studied

- Acute Circulatory Failure

## Interventions

- **OTHER:** Fluid loading of 500 mL of crystalloid solution
- **OTHER:** Passive Leg Raising test

## Key facts

- **NCT ID:** NCT03225378
- **Lead sponsor:** Centre Hospitalier Arras
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2017-09-21
- **Primary completion:** 2021-09-20
- **Final completion:** 2021-09-20
- **Target enrollment:** 286 (ACTUAL)
- **Last updated:** 2021-10-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03225378

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03225378, "Changes in PPV Induced by PLR Test to Predict Fluid Responsiveness in ICU". Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/clinical/NCT03225378. Licensed CC0.

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