# Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia

> **NCT03226418** · PHASE2 · COMPLETED · sponsor: **University of Nebraska** · enrollment: 75 (actual)

## Conditions studied

- Adult Acute Myeloid Leukemia
- Secondary Acute Myeloid Leukemia
- Therapy-Related Acute Myeloid Leukemia

## Interventions

- **DRUG:** Cytarabine
- **DRUG:** Decitabine
- **DRUG:** Idarubicin
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Liposome-encapsulated Daunorubicin-Cytarabine
- **OTHER:** Quality-of-Life Assessment
- **OTHER:** Questionnaire Administration
- **DRUG:** Azacitidine
- **DRUG:** Venetoclax
- **DRUG:** glasdegib

## Key facts

- **NCT ID:** NCT03226418
- **Lead sponsor:** University of Nebraska
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-07-07
- **Primary completion:** 2024-03-16
- **Final completion:** 2024-10-01
- **Target enrollment:** 75 (ACTUAL)
- **Last updated:** 2026-03-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03226418

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03226418, "Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT03226418. Licensed CC0.

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