Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

NCT03228537 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

28

Enrollment

NIH

Sponsor class

Conditions

Biphasic Mesothelioma
Epithelioid Mesothelioma
Stage I Pleural Diffuse Malignant Mesothelioma AJCC v7
Stage IA Pleural Diffuse Malignant Mesothelioma AJCC v7
Stage IB Pleural Diffuse Malignant Mesothelioma AJCC v7
Stage II Pleural Diffuse Malignant Mesothelioma AJCC v7
Stage III Pleural Diffuse Malignant Mesothelioma AJCC v7

Interventions

DRUG: Atezolizumab
DRUG: Cisplatin
PROCEDURE: Extrapleural Pneumonectomy
DRUG: Pemetrexed Disodium
PROCEDURE: Pleurectomy
RADIATION: Radiation Therapy

Sponsor

National Cancer Institute (NCI)