# Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas

> **NCT03231306** · PHASE2 · COMPLETED · sponsor: **University of Alabama at Birmingham** · enrollment: 45 (actual)

## Conditions studied

- Neurofibromatosis Type 1
- Plexiform Neurofibroma

## Interventions

- **DRUG:** Binimetinib

## Key facts

- **NCT ID:** NCT03231306
- **Lead sponsor:** University of Alabama at Birmingham
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-11-28
- **Primary completion:** 2024-04-17
- **Final completion:** 2024-04-17
- **Target enrollment:** 45 (ACTUAL)
- **Last updated:** 2025-05-02

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03231306

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03231306, "Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT03231306. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*