# Efficacy and Safety of E-cigarettes for Smoking Cessation in Middle-aged Heavy Smokers

> **NCT03235505** · PHASE4 · COMPLETED · sponsor: **University of Oulu** · enrollment: 450 (actual)

## Conditions studied

- Smoking Cessation
- Electronic Cigarette

## Interventions

- **DRUG:** Nicotine
- **DRUG:** Varenicline Tartrate
- **BEHAVIORAL:** Motivational Interview

## Key facts

- **NCT ID:** NCT03235505
- **Lead sponsor:** University of Oulu
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-08-01
- **Primary completion:** 2021-03-31
- **Final completion:** 2021-03-31
- **Target enrollment:** 450 (ACTUAL)
- **Last updated:** 2024-05-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03235505

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03235505, "Efficacy and Safety of E-cigarettes for Smoking Cessation in Middle-aged Heavy Smokers". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT03235505. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*