# A Blood Stem Cell Transplant for Sickle Cell Disease

> **NCT03249831** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **City of Hope Medical Center** · enrollment: 3 (actual)

## Conditions studied

- Sickle Cell Disease
- Sickle Cell Disorder
- Hemoglobinopathies
- Thalassemia
- Anemia, Sickle Cell

## Interventions

- **DRUG:** Cyclophosphamide
- **DRUG:** Pentostatin
- **DRUG:** Rabbit anti-thymocyte globulin
- **DRUG:** Tacrolimus
- **DRUG:** Mycophenolate mofetil
- **BIOLOGICAL:** CD4+ T-cell-depleted Haploidentical Hematopoietic Transplant

## Key facts

- **NCT ID:** NCT03249831
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2019-01-04
- **Primary completion:** 2027-01-25
- **Final completion:** 2027-01-25
- **Target enrollment:** 3 (ACTUAL)
- **Last updated:** 2026-03-05

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03249831

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03249831, "A Blood Stem Cell Transplant for Sickle Cell Disease". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03249831. Licensed CC0.

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