# N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes

> **NCT03253328** · EARLY_PHASE1 · COMPLETED · sponsor: **Washington University School of Medicine** · enrollment: 33 (actual)

## Conditions studied

- Diabetes Mellitus
- Critical Limb Ischemia
- Lower Limb Amputation Knee
- Peripheral Arterial Disease

## Interventions

- **DRUG:** Active Arm N-acetyl cysteine (NAC)
- **DRUG:** Placebo Arm

## Key facts

- **NCT ID:** NCT03253328
- **Lead sponsor:** Washington University School of Medicine
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-03-01
- **Primary completion:** 2021-08-31
- **Final completion:** 2022-06-27
- **Target enrollment:** 33 (ACTUAL)
- **Last updated:** 2024-08-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03253328

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03253328, "N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes". Retrieved via AI Analytics 2026-05-30 from https://api.ai-analytics.org/clinical/NCT03253328. Licensed CC0.

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