# Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

> **NCT03255408** · PHASE1,PHASE2 · RECRUITING · sponsor: **University of Calgary** · enrollment: 12 (estimated)

## Conditions studied

- Obstructive Sleep Apnea of Adult
- Hypoxia, Brain
- Sleep Apnea
- Sleep Disorder
- Stroke
- Blood Pressure
- Endothelial Dysfunction
- Oxidative Stress

## Interventions

- **DRUG:** Drug Lowering Cerebral Blood Flow (CBF) and Normoxia Sleep
- **DRUG:** Drug Lowering CBF and Intermittent Hypoxia Sleep
- **DRUG:** Placebo and Normoxia Sleep
- **DRUG:** Placebo and Intermittent Hypoxia Sleep

## Key facts

- **NCT ID:** NCT03255408
- **Lead sponsor:** University of Calgary
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-01-01
- **Primary completion:** 2027-12-30
- **Final completion:** 2027-12-30
- **Target enrollment:** 12 (ESTIMATED)
- **Last updated:** 2026-05-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03255408

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03255408, "Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03255408. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*