# Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency Department

> **NCT03257319** · PHASE3 · COMPLETED · sponsor: **University Hospital, Rouen** · enrollment: 226 (actual)

## Conditions studied

- Pain, Acute
- Emergencies
- Morphine

## Interventions

- **DRUG:** inhaled titration of morphine chlorhydrate
- **DRUG:** IV placebo
- **DEVICE:** Inhaled placebo
- **DRUG:** IV titration of morphine chlorhydrate

## Key facts

- **NCT ID:** NCT03257319
- **Lead sponsor:** University Hospital, Rouen
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-09-19
- **Primary completion:** 2022-07-29
- **Final completion:** 2022-07-29
- **Target enrollment:** 226 (ACTUAL)
- **Last updated:** 2026-02-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03257319

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03257319, "Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency Department". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03257319. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*