Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant

NCT03259503 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

50

Enrollment

OTHER

Sponsor class

Conditions

Recurrent Diffuse Large B-Cell Lymphoma
Recurrent T-Cell Non-Hodgkin Lymphoma
Refractory Diffuse Large B-Cell Lymphoma
Refractory Hodgkin Lymphoma
Refractory T-Cell Non-Hodgkin Lymphoma

Interventions

DRUG: Busulfan
DRUG: Gemcitabine
DRUG: Melphalan
DRUG: Olaparib
PROCEDURE: Peripheral Blood Stem Cell Transplantation
OTHER: Pharmacokinetic Study
BIOLOGICAL: Rituximab
DRUG: Vorinostat

Sponsor

M.D. Anderson Cancer Center

Collaborators

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