# Cardiovagal Baroreflex Deficits Impair Neurovascular Coupling and Cognition in POTS

> **NCT03261570** · EARLY_PHASE1 · COMPLETED · sponsor: **New York Medical College** · enrollment: 51 (actual)

## Conditions studied

- Postural Orthostatic Tachycardia Syndrome (POTS)
- POTS
- Orthostatic Intolerance

## Interventions

- **DRUG:** Pyridostigmine
- **DRUG:** Digoxin
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT03261570
- **Lead sponsor:** New York Medical College
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-07-01
- **Primary completion:** 2022-06-01
- **Final completion:** 2022-06-01
- **Target enrollment:** 51 (ACTUAL)
- **Last updated:** 2022-09-28

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03261570

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03261570, "Cardiovagal Baroreflex Deficits Impair Neurovascular Coupling and Cognition in POTS". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT03261570. Licensed CC0.

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