# Study of Safety, Tolerability, Preliminary Efficacy of Intra-articular LNA043 Injections in Patients With Articular Cartilage Lesions and Knee Osteoarthritis.

> **NCT03275064** · PHASE2 · COMPLETED · sponsor: **Novartis Pharmaceuticals** · enrollment: 142 (actual)

## Conditions studied

- Osteoarthritis

## Interventions

- **BIOLOGICAL:** LNA043
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT03275064
- **Lead sponsor:** Novartis Pharmaceuticals
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-09-12
- **Primary completion:** 2022-09-06
- **Final completion:** 2022-09-06
- **Target enrollment:** 142 (ACTUAL)
- **Last updated:** 2026-04-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03275064

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03275064, "Study of Safety, Tolerability, Preliminary Efficacy of Intra-articular LNA043 Injections in Patients With Articular Cartilage Lesions and Knee Osteoarthritis.". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03275064. Licensed CC0.

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