# An Efficacy and Safety Study of Ontamalimab as Maintenance Therapy in Participants With Moderate to Severe Ulcerative Colitis

> **NCT03290781** · PHASE3 · COMPLETED · sponsor: **Shire** · enrollment: 366 (actual)

## Conditions studied

- Ulcerative Colitis

## Interventions

- **DRUG:** Ontamalimab
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT03290781
- **Lead sponsor:** Shire
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-04-04
- **Primary completion:** 2021-07-01
- **Final completion:** 2021-07-01
- **Target enrollment:** 366 (ACTUAL)
- **Last updated:** 2022-01-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03290781

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03290781, "An Efficacy and Safety Study of Ontamalimab as Maintenance Therapy in Participants With Moderate to Severe Ulcerative Colitis". Retrieved via AI Analytics 2026-05-30 from https://api.ai-analytics.org/clinical/NCT03290781. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*