# Opioid Induced Loss of Local Anesthetic Potency in Patients Undergoing Total Knee Arthroplasty

> **NCT03294174** · — · TERMINATED · sponsor: **University of Pittsburgh** · enrollment: 48 (actual)

## Conditions studied

- Opioid Tolerance, Opioid Naive, Opioid Exposure

## Interventions

- **DRUG:** Ropivacaine injection

## Key facts

- **NCT ID:** NCT03294174
- **Lead sponsor:** University of Pittsburgh
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** TERMINATED
- **Start date:** —
- **Primary completion:** 2017-06
- **Final completion:** 2017-06
- **Target enrollment:** 48 (ACTUAL)
- **Why stopped:** Responsible Investigator left institution
- **Last updated:** 2018-11-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03294174

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03294174, "Opioid Induced Loss of Local Anesthetic Potency in Patients Undergoing Total Knee Arthroplasty". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03294174. Licensed CC0.

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