# Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity

> **NCT03318094** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Vanderbilt University Medical Center** · enrollment: 36 (estimated)

## Conditions studied

- Insulin Resistance
- Healthy
- Obesity

## Interventions

- **DRUG:** Phentolamine
- **OTHER:** Saline
- **DRUG:** Sodium Nitroprusside

## Key facts

- **NCT ID:** NCT03318094
- **Lead sponsor:** Vanderbilt University Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2017-10-24
- **Primary completion:** 2026-11-30
- **Final completion:** 2027-11-30
- **Target enrollment:** 36 (ESTIMATED)
- **Last updated:** 2026-03-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03318094

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03318094, "Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03318094. Licensed CC0.

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