# Blood-Brain Barrier Opening Using MR-Guided Focused Ultrasound in Patients With Amyotrophic Lateral Sclerosis

> **NCT03321487** · NA · COMPLETED · sponsor: **InSightec** · enrollment: 4 (actual)

## Conditions studied

- Amyotrophic Lateral Sclerosis

## Interventions

- **DEVICE:** Blood-Brain Barrier opening with MRgFUS

## Key facts

- **NCT ID:** NCT03321487
- **Lead sponsor:** InSightec
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-04-13
- **Primary completion:** 2021-12-30
- **Final completion:** 2023-09-11
- **Target enrollment:** 4 (ACTUAL)
- **Last updated:** 2026-03-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03321487

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03321487, "Blood-Brain Barrier Opening Using MR-Guided Focused Ultrasound in Patients With Amyotrophic Lateral Sclerosis". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT03321487. Licensed CC0.

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