# Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Geriatric Patients Undergoing Total Knee Replacement Under Spinal Anesthesia

> **NCT03322098** · NA · COMPLETED · sponsor: **Yonsei University** · enrollment: 54 (actual)

## Conditions studied

- Spinal Anesthesia

## Interventions

- **DRUG:** Atropine
- **DRUG:** Glycopyrrolate

## Key facts

- **NCT ID:** NCT03322098
- **Lead sponsor:** Yonsei University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-10-16
- **Primary completion:** 2018-05-15
- **Final completion:** 2018-05-15
- **Target enrollment:** 54 (ACTUAL)
- **Last updated:** 2018-09-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03322098

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03322098, "Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Geriatric Patients Undergoing Total Knee Replacement Under Spinal Anesthesia". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT03322098. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*