Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer
Conditions
Interventions
- DRUG: CYP1A2 (caffeine)
- DRUG: CYP2C19 (omeprazole)
- DRUG: CYP3A (midazolam)
- DRUG: Kytril (granisetron)
- DRUG: Wee-1 kinase inhibitor AZD1775
Sponsor
AstraZeneca
Collaborators