Adoptive Cellular Therapy in Pediatric Patients With High-grade Gliomas

NCT03334305 · clinicaltrials.gov ↗

PHASE1

Phase

TERMINATED

Status

18

Enrollment

OTHER

Sponsor class

Stopped due to lack of accrual/feasibility to complete accrual due to competing trials

Conditions

Malignant Glioma
High Grade Glioma

Interventions

BIOLOGICAL: TTRNA-DC vaccines with GM-CSF
DRUG: Dose-intensified TMZ
BIOLOGICAL: Autologous Hematopoietic Stem cells (HSCs)
BIOLOGICAL: TTRNA-xALT
DRUG: Td vaccine

Sponsor

University of Florida

Collaborators

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