# AT1R Blockade and Periodic Breathing During Sleep in Hypoxia

> **NCT03335904** · PHASE4 · COMPLETED · sponsor: **University of British Columbia** · enrollment: 14 (actual)

## Conditions studied

- Sleep Disordered Breathing
- Hypoxia
- Respiration; Sleep Disorder
- Chemoreceptor Apnea

## Interventions

- **OTHER:** Hyperoxic Hypercapnic Ventilatory Response Test
- **OTHER:** Hypoxic Hypercapnic Ventilatory Response Test
- **OTHER:** Repeated Hypoxic Apneas
- **OTHER:** Hypoxic Sleep Study
- **DRUG:** Losartan
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT03335904
- **Lead sponsor:** University of British Columbia
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-01-01
- **Primary completion:** 2019-08-01
- **Final completion:** 2019-08-01
- **Target enrollment:** 14 (ACTUAL)
- **Last updated:** 2020-09-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03335904

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03335904, "AT1R Blockade and Periodic Breathing During Sleep in Hypoxia". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT03335904. Licensed CC0.

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