# Assessment of Change in CYP3A Activity by Route of Administration Using Metabolic Markers in Healthy Male Volunteers

> **NCT03366974** · PHASE1 · COMPLETED · sponsor: **Seoul National University Hospital** · enrollment: 16 (actual)

## Conditions studied

- Healthy Volunteers

## Interventions

- **DRUG:** Midazolam
- **DRUG:** Clarithromycin
- **DIETARY_SUPPLEMENT:** Grapefruit juice

## Key facts

- **NCT ID:** NCT03366974
- **Lead sponsor:** Seoul National University Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-12-28
- **Primary completion:** 2018-02-13
- **Final completion:** 2018-12-12
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2022-10-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03366974

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03366974, "Assessment of Change in CYP3A Activity by Route of Administration Using Metabolic Markers in Healthy Male Volunteers". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT03366974. Licensed CC0.

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