# Cooled Radiofrequency vs. Hyaluronic Acid to Manage Knee Pain

> **NCT03381248** · NA · COMPLETED · sponsor: **Avanos Medical** · enrollment: 177 (actual)

## Conditions studied

- Osteoarthritis of the Knee

## Interventions

- **DEVICE:** Cooled Radiofrequency
- **OTHER:** Hyaluronic Acid Injection
- **OTHER:** Crossover from Hyaluronic Acid Injection to Cooled Radiofrequency

## Key facts

- **NCT ID:** NCT03381248
- **Lead sponsor:** Avanos Medical
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-12-07
- **Primary completion:** 2019-02-08
- **Final completion:** 2020-07-20
- **Target enrollment:** 177 (ACTUAL)
- **Last updated:** 2023-10-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03381248

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03381248, "Cooled Radiofrequency vs. Hyaluronic Acid to Manage Knee Pain". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT03381248. Licensed CC0.

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